GeneTex
United States (US)

GPX4 antibody

GTX54095_20180530_WB_18121410_720.jpg
GTX54095_20180530_IHC-P_18121410_358.jpg
GTX54095_20180530_IHC-P_1_18121410_821.jpg

Cat No. GTX54095

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

22 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 30-197 of human GPX4 (NP_002076.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

MCSP Antibody , GSHPX4 Antibody , SNPHGPX Antibody , PHGPX Antibody , SNGPX Antibody

Background

This gene encodes a member of the glutathione peroxidase protein family. Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. The encoded protein has been identified as a moonlighting protein based on its ability to serve dual functions as a peroxidase as well as a structural protein in mature spermatozoa. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Database

Research Area

DATA IMAGES
GTX54095_20180530_WB_18121410_720.jpg

GTX54095 WB Image

WB analysis of various samples using GTX54095 GPX4 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX54095_20180530_IHC-P_18121410_358.jpg

GTX54095 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX54095 GPX4 antibody.
Dilution : 1:200

GTX54095_20180530_IHC-P_1_18121410_821.jpg

GTX54095 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX54095 GPX4 antibody.
Dilution : 1:200

Package List Price ($)
$ 319