Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 1:500-1:3000 |
| 1:100-1:1000 |
Not tested in other applications.
Calculated MW
Positive Control
Jurkat
Predict Reactivity
Mouse, Rat, Bovine, Rhesus Monkey(>80% identity)
Form
Liquid
Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.)
Concentration
0.7mg/ml
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human GRAP2. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Synonyms
GADS antibody, GRAP-2 antibody, GRB2L antibody, GRBLG antibody, GRID antibody, GRPL antibody, GrbX antibody, Grf40 antibody, Mona antibody, P38 antibody, GRAP2 antibody, hematopoietic cell-associated adapter protein GrpL antibody, growth factor receptor-binding protein antibody, SH3-SH2-SH3 adaptor molecule antibody, growth factor receptor-bound protein 2-related adaptor protein 2 antibody, GRB-2-like protein antibody, grf-40 antibody, GRB2-related adapter protein 2 antibody, GRB2-related protein with insert domain antibody, grf40 adapter protein antibody, hematopoietic cell-associated adaptor protein GRPL antibody, SH3-SH2-SH3 adapter Mona antibody, adapter protein GRID antibody, GRB2-related adaptor protein 2 antibody
Background
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq]
Database
Research Area
