GeneTex
United States (US)

GRAP2 antibody

GTX115233_40254_IHC_18121410_641.jpg
GTX115233_WB_18121410_878.jpg

Cat No. GTX115233

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Positive Control

Jurkat

Predict Reactivity

Mouse, Rat, Bovine, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.)

Concentration

0.7mg/ml

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human GRAP2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

GADS antibody, GRAP-2 antibody, GRB2L antibody, GRBLG antibody, GRID antibody, GRPL antibody, GrbX antibody, Grf40 antibody, Mona antibody, P38 antibody, GRAP2 antibody, hematopoietic cell-associated adapter protein GrpL antibody, growth factor receptor-binding protein antibody, SH3-SH2-SH3 adaptor molecule antibody, growth factor receptor-bound protein 2-related adaptor protein 2 antibody, GRB-2-like protein antibody, grf-40 antibody, GRB2-related adapter protein 2 antibody, GRB2-related protein with insert domain antibody, grf40 adapter protein antibody, hematopoietic cell-associated adaptor protein GRPL antibody, SH3-SH2-SH3 adapter Mona antibody, adapter protein GRID antibody, GRB2-related adaptor protein 2 antibody

Background

This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq]
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Database

Research Area

DATA IMAGES
GTX115233_40254_IHC_18121410_641.jpg

GTX115233 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using GRAP2(GTX115233) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX115233_WB_18121410_878.jpg

GTX115233 WB Image

Sample (30 ug of whole cell lysate)
A: JurKat
10% SDS PAGE
GTX115233 diluted at 1:1000

SDS
Glycerol.pdf
Thimerosal.pdf