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GRB2 antibody [3B2-G2-E5]

Anti-GRB2 antibody [3B2-G2-E5] used in Western Blot (WB). GTX49267
Anti-GRB2 antibody [3B2-G2-E5] used in Western Blot (WB). GTX49267

Cat No. GTX49267

Host

Mouse

Clonality

Monoclonal

Clone Name

3B2-G2-E5

Isotype

IgG1

Application

WB

Reactivity

Human, Mouse, Rat, Monkey
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human GRB2 protein fragments expressed in E.coli.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Growth Factor Receptor Bound Protein 2 , Ash , Egfrbp-Grb2 , Grb3-3 , Mst084 , Mstp084 , Nckap2 , Grb2

Cellular Localization

Nucleus. Cytoplasm. Endosome. Golgi apparatus By similarity.

Background

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GRB2 antibody [3B2-G2-E5] used in Western Blot (WB). GTX49267

GTX49267 WB Image

WB analysis of 3T3, PC12, Raji and Jurkat lysates using GRB2 antibody at a dilution of 1:500.

Anti-GRB2 antibody [3B2-G2-E5] used in Western Blot (WB). GTX49267

GTX49267 WB Image

WB analysis of indicated lysates using GRB2 antibody at a dilution of 1:300.

REFERENCE

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REVIEW

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