GeneTex
United States (US)

GRB2 antibody

GTX32632_20180530_WB_18121410_766.jpg
GTX32632_20180530_IHC-P_18121410_576.jpg

Cat No. GTX32632

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

25 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GRB2 (NP_002077.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Growth Factor Receptor Bound Protein 2,Ash,Egfrbp-Grb2,Grb3-3,Mst084,Mstp084,Nckap2,Grb2

Background

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX32632_20180530_WB_18121410_766.jpg

GTX32632 WB Image

WB analysis of various samples using GTX32632 GRB2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX32632_20180530_IHC-P_18121410_576.jpg

GTX32632 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX32632 GRB2 antibody.
Dilution : 1:100

Package List Price ($)
$ 329