GeneTex
United States (US)

GREM2 antibody

GTX16272_WB_18121410_942.jpg

Cat No. GTX16272

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

Western blotting (0.5-4 μg/ml).

Calculated MW

19 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS containing 30% glycerol, pH 7.2, 0.5% BSA, 0.01% thimerosal.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Gremlin 2, Dan Family Bmp Antagonist,Cktsf1B2,Dand3,Prdc,Sthag9,Grem2

Background

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX16272_WB_18121410_942.jpg

GTX16272 WB Image

WB analysis of recombinant human Gremlin-2. Lane 1: 5 ng, Lane 2: 10 ng, Lane 3: 50 ng, Lane 4: 100 ng.

Package List Price ($)
$ 329