GeneTex
United States (US)

GRIM19 antibody

Cat No. GTX30483

Host Rabbit
Clonality Polyclonal
Application WB
Reactivity Human
APPLICATION

Calculated MW

17 kDa. ( Note )

Specificity/Sensitivity

Reacts with the human GRIM-19 protein.
PROPERTIES

Form

Liquid

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide to human GRIM-19 (QAETDRRTLQMLRE).

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Nadh:Ubiquinone Oxidoreductase Subunit A13,B16.6,Cda016,Cgi-39,Grim-19,Grim19,Ndufa13

Background

A novel gene, Genes associated with Retinoid-IFN-induced Mortality (GRIM) GRIM-19 gene was identified. Antisense expression of GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM-19 is a novel cell death-regulatory molecule.

Database

Research Area

Package List Price ($)
$ 289