GeneTex
United States (US)

GRK2 antibody [5D5]

Cat No. GTX30211

Host Mouse
Clonality Monoclonal
Clone Name 5D5
Isotype IgG1
Application WB, IHC
Reactivity Human, Rat, Bovine
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:100
IHC 1:100
Not tested in other applications.

Calculated MW

80 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human GRK2. [UniProt# P25098]

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

G Protein-Coupled Receptor Kinase 2,Adrbk1,Bark1,Beta-Ark1,Grk2

Background

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq]

Database

Research Area

Package List Price ($)
$ 319