GeneTex
United States (US)

GSK3 beta antibody

GTX37303_20190129_ICCIF_19012901_425.jpg
GTX37303_20190129_IHC-P_19012901_207.jpg
GTX37303_20190129_WB_19012901_383.jpg

Cat No. GTX37303

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
ICC/IF 1:100-1:200
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

47 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS (without Mg2+ and Ca2+) pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized non-phosphopeptide derived from human GSK3 beta around the phosphorylation site of serine 9 (T -T-S(p)-F-A).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Glycogen Synthase Kinase 3 Beta,Gsk3B

Cellular Localization

Cell membrane,Cytoplasm,Nucleus

Background

The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES
GTX37303_20190129_ICCIF_19012901_425.jpg

GTX37303 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX37303 GSK3 beta antibody.

GTX37303_20190129_IHC-P_19012901_207.jpg

GTX37303 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX37303 GSK3 beta antibody.

GTX37303_20190129_WB_19012901_383.jpg

GTX37303 WB Image

WB analysis of A2780 and HT-29 cell lysates using GTX37303 GSK3 beta antibody.

Package List Price ($)
$ 219