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Galectin 13 antibody [PP13/1161]

Anti-Galectin 13 antibody [PP13/1161] used in IHC (Paraffin sections) (IHC-P). GTX34747
Anti-Galectin 13 antibody [PP13/1161] used in IHC (Paraffin sections) (IHC-P). GTX34747
Anti-Galectin 13 antibody [PP13/1161] used in Western Blot (WB). GTX34747

Cat No. GTX34747

Host Mouse
Clonality Monoclonal
Clone Name PP13/1161
Isotype IgG2b
Application WB, ICC/IF, IHC-P
Reactivity Human
Package
100 μg ($429)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-1ug/ml
ICC/IF 0.5-1ug/ml
IHC-P 0.5-1ug/ml for 30 minutes at RT

Note :

IHC-P
Boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 or 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes

Not tested in other applications.

Calculated MW

16 kDa. ( Note )

Specificity/Sensitivity

It recognizes a 32kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble β-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
PROPERTIES

Form

Liquid

Buffer

1mM PBS with 0.05% BSA, 0.05% azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml

Antigen Species

Human

Immunogen

Recombinant human Galectin-13 protein fragment (aa23-134) (exact sequence is proprietary)

Purification

Ab purified from Bioreactor Concentrate by Protein A/G

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Galectin 13 , Gal13 , Plac8 , Pp13 , Lgals13

Background

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene has lysophospholipase activity. It is composed of two identical subunits which are held together by disulfide bonds. This protein has structural similarity to several members of the beta-galactoside-binding S-type lectin family. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-Galectin 13 antibody [PP13/1161] used in IHC (Paraffin sections) (IHC-P). GTX34747

GTX34747 IHC-P Image

Formalin-paraffin human Spleen stained with Galectin-13MAb (PP13/1161).

Anti-Galectin 13 antibody [PP13/1161] used in IHC (Paraffin sections) (IHC-P). GTX34747

GTX34747 IHC-P Image

Formalin-paraffin human Placenta stained with Galectin-13 MAb (PP13/1161).

Anti-Galectin 13 antibody [PP13/1161] used in Western Blot (WB). GTX34747

GTX34747 WB Image

Western Blot of (A) Recombinant human Galectin-13 fragment And (B) K562 Cell Lysate using Galeactin-13 MAb (PP13/1161).

REFERENCE
There are currently no references for Galectin 13 antibody [PP13/1161] (GTX34747). Be the first to share your publications with this product.
REVIEW
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Package List Price ($)
$ 429