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Gasdermin B antibody [N1C1]

Anti-Gasdermin B antibody [N1C1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX117760
Anti-Gasdermin B antibody [N1C1] used in Western Blot (WB). GTX117760

Cat. No. GTX117760

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all Gasdermin B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Positive Control

HeLa

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.45 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human Gasdermin B. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10617458

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

gasdermin B , GSDML , PP4052 , PRO2521

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-Gasdermin B antibody [N1C1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX117760

GTX117760 ICC/IF Image

Immunofluorescence analysis of methanol-fixed HeLa, using Gasdermin-B(GTX117760) antibody at 1:500 dilution.

Anti-Gasdermin B antibody [N1C1] used in Western Blot (WB). GTX117760

GTX117760 WB Image

Sample (30 ug of whole cell lysate)
A: Hela
10% SDS PAGE
GTX117760 diluted at 1:1000

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169