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Gasdermin C antibody

Anti-Gasdermin C antibody used in Western Blot (WB). GTX33979

Cat. No. GTX33979

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all Gasdermin C products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthesized peptide derived from human Gasdermin C at 80-160 aa, Internal.

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

GSDMC,MLZE,gasdermin C,Gasdermin C

Cellular Localization

Cytoplasm,Cytosol,Cell membrane

Database

Research Area

DATA IMAGES

Anti-Gasdermin C antibody used in Western Blot (WB). GTX33979

GTX33979 WB Image

WB analysis of 293 cell lysate using GTX33979 Gasdermin C antibody.

REFERENCE

Application Reference

S Wang et al. The Journal of Clinical Investigation 2023; : e166841 Gasdermin C sensitizes tumor cells to PARP inhibitor therapy in cancer models
Xia XH et al. Am J Cancer Res 2023; 13 (4) : 1240-1258 The expression profile of Gasdermin C-related genes predicts the prognosis and immunotherapy response of pancreatic adenocarcinoma.
Junwei Hou et al. Nat Cell Biol 2020; 22 (10) : 1264-1275 PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis
Application : IHC-P
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399