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Gasdermin D antibody [HL1430]

Recombinant antibody Orthogonal
Anti-Gasdermin D antibody [HL1430] used in Western Blot (WB). GTX636896
Anti-Gasdermin D antibody [HL1430] used in IHC (Paraffin sections) (IHC-P). GTX636896

Cat. No. GTX636896

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL1430

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all Gasdermin D products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of Human Gasdermin D. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

gasdermin D , DF5L , DFNA5L , FKSG10 , GSDMDC1

Cellular Localization

Secreted

Background

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES

Anti-Gasdermin D antibody [HL1430] used in Western Blot (WB). GTX636896

GTX636896 WB Image

Orthogonal

Untreated (–) and treated (+) THP-1 whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Gasdermin D antibody [HL1430] (GTX636896) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Gasdermin D antibody [HL1430] used in IHC (Paraffin sections) (IHC-P). GTX636896

GTX636896 IHC-P Image

Gasdermin D antibody [HL1430] detects Gasdermin D protein at cell membrane and secreted by immunohistochemical analysis.
Sample: Paraffin-embedded human breast carcinoma.
Gasdermin D stained by Gasdermin D antibody [HL1430] (GTX636896) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
Custom Conjugations