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Ghrelin antibody [121] (Biotin)

Anti-Ghrelin antibody [121] (Biotin) used in ELISA (ELISA). GTX60947-02

Cat. No. GTX60947-02

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 121

Isotype

 IgG2b

Application

 ELISA

Reactivity

 Human, Mouse, Rat, Cat, Dog
Package
50 μl ($799)
See all Ghrelin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ELISA Assay dependent
Not tested in other applications.

Calculated MW

13 kDa. ( Note )

Product Note

This antibody binds human ghrelin.

PROPERTIES

Form

Liquid

Buffer

0.01M Phosphate buffer pH7.4, 0.14M NaCl

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Synthetic ghrelin (14-28)

Purification

Biotinylated

Conjugation

Biotin

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ghrelin and obestatin prepropeptide , MTLRP

Cellular Localization

Secreted

Background

This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]

Database

Research Area

DATA IMAGES

Anti-Ghrelin antibody [121] (Biotin) used in ELISA (ELISA). GTX60947-02

GTX60947-02 ELISA Image

The calibration curve of a sandwich assay for Ghrelin using GTX60946 as the capture antibody and GTX60947- 02 as the biotinylated detection antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 799