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Ghrelin antibody [45]

Anti-Ghrelin antibody [45] used in ELISA (ELISA). GTX60946

Cat No. GTX60946

Host

Mouse

Clonality

Monoclonal

Clone Name

45

Isotype

IgG1

Application

WB, ELISA

Reactivity

Human, Rat
Package
100 μl ($499)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

13 kDa. ( Note )

Product Note

This antibody binds human octanoylated ghrelin and human des-acyl ghrelin.

PROPERTIES

Form

Liquid

Buffer

0.01M Phosphate buffer pH7.4, 0.5M NaCl

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic human Ser3-octanoyl ghrelin-28

Purification

Protein-A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ghrelin and obestatin prepropeptide , MTLRP

Cellular Localization

Secreted

Background

This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]

Database

Research Area

DATA IMAGES

Anti-Ghrelin antibody [45] used in ELISA (ELISA). GTX60946

GTX60946 ELISA Image

The calibration curve of a sandwich assay for Ghrelin using GTX60946 as the capture antibody and GTX60947- 02 as the biotinylated detection antibody.

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 499