PBS, 0.02% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Immunogen Sequence: GI # 19224664, sequence 38-49 Synthetic peptide sequence of ghrelin (Mus musculus).
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release from the pituitary. It has an appetite stimulating effect, induces adiposity, and stimulates gastric acid secretion, and it is involved in growth regulation. Ghrelin is synthesized as a preprohormone, then proteolytically processed to yield a 28 amino acid peptide. An interesting and unique modification is imposed on the hormone during synthesis in the form of an n octanoic acid bound to one of its amino acids. This modification is necessary for biologic activity.