*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol
0.02% Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Peptide sequence around phosphorylation site of Serine 1417(Q-K-S(p)-L-T) derived from human Girdin.
Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
coiled-coil domain containing 88A , APE , GIRDIN , GIV , GRDN , HkRP1 , KIAA1212 , PEHO , PEHOL
Membrane,Cell membrane,Cytoplasm, cytosol,Cytoplasmic vesicle
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
GTX55363 IHC-P Image
IHC-P analysis of human breast carcinoma tissue using GTX55363 Girdin (phospho Ser1417) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide
There are currently no references for Girdin (phospho Ser1417) antibody (GTX55363). Be the first to share your publications with this product.
There are currently no reviews for Girdin (phospho Ser1417) antibody (GTX55363). Be the first to share your experience with this product.