GeneTex

  • Country / Location Selection

United States (US)

GluR2 antibody [7G6]

Anti-GluR2 antibody [7G6] used in ELISA (ELISA). GTX60613
Anti-GluR2 antibody [7G6] used in Western Blot (WB). GTX60613
Anti-GluR2 antibody [7G6] used in Flow cytometry (FACS). GTX60613
Anti-GluR2 antibody [7G6] used in Western Blot (WB). GTX60613

Cat. No. GTX60613

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7G6

Isotype

 IgG1

Application

 WB, FACS, ELISA

Reactivity

 Human
Package
100 μg ($409)
See all GluR2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant fragment of human GluR2 (AA: 652-807) expressed in E. Coli.

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glutamate ionotropic receptor AMPA type subunit 2 , GLUR2 , GLURB , GluA2 , GluR-K2 , HBGR2

Cellular Localization

Cell membrane,Endoplasmic reticulum membrane

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GluR2 antibody [7G6] used in ELISA (ELISA). GTX60613

GTX60613 ELISA Image

ELISA analysis of antigen using GTX60613 GluR2 antibody [7G6].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng

Anti-GluR2 antibody [7G6] used in Western Blot (WB). GTX60613

GTX60613 WB Image

WB analysis of HeLa cell lysate using GTX60613 GluR2 antibody [7G6].

Anti-GluR2 antibody [7G6] used in Flow cytometry (FACS). GTX60613

GTX60613 FACS Image

FACS analysis of SK-N-SH cells using GTX60613 GluR2 antibody [7G6].
Green : GluR2
Red : negative control

Anti-GluR2 antibody [7G6] used in Western Blot (WB). GTX60613

GTX60613 WB Image

WB analysis of HEK293 (1) and GluR2 (AA: 652-807)-hIgGFc transfected HEK293 (2) cell lysate using GTX60613 GluR2 antibody [7G6].

REFERENCE

There are currently no references for GluR2 antibody [7G6] (GTX60613). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for GluR2 antibody [7G6] (GTX60613). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409