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GluR2 antibody [GT1283]

Recombinant antibody
Anti-GluR2 antibody [GT1283] used in Western Blot (WB). GTX03195
Anti-GluR2 antibody [GT1283] used in Western Blot (WB). GTX03195
Anti-GluR2 antibody [GT1283] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX03195
Anti-GluR2 antibody [GT1283] used in IHC (Paraffin sections) (IHC-P). GTX03195
Anti-GluR2 antibody [GT1283] used in IHC (Paraffin sections) (IHC-P). GTX03195
Anti-GluR2 antibody [GT1283] used in IHC (Paraffin sections) (IHC-P). GTX03195
Anti-GluR2 antibody [GT1283] used in IHC (Paraffin sections) (IHC-P). GTX03195
Anti-GluR2 antibody [GT1283] used in Western Blot (WB). GTX03195

Cat. No. GTX03195

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GT1283

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($439)
See all GluR2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.3 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human GluR2.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glutamate ionotropic receptor AMPA type subunit 2 , GLUR2 , GLURB , GluA2 , GluR-K2 , HBGR2

Cellular Localization

Cell membrane , Endoplasmic reticulum membrane

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GluR2 antibody [GT1283] used in Western Blot (WB). GTX03195

GTX03195 WB Image

Various tissue extracts (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GluR2 antibody [GT1283] (GTX03195) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-GluR2 antibody [GT1283] used in Western Blot (WB). GTX03195

GTX03195 WB Image

Human tissue extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with GluR2 antibody [GT1283] (GTX03195) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-GluR2 antibody [GT1283] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX03195

GTX03195 ICC/IF Image

ICC/IF analysis of SH-SY5Y cells using GTX03195 GluR2 antibody [GT1283].
Blue : DAPI for nuclear staining
Dilution : 1:100

Anti-GluR2 antibody [GT1283] used in IHC (Paraffin sections) (IHC-P). GTX03195

GTX03195 IHC-P Image

IHC-P analysis of mouse brain tissue section using GTX03195 GluR2 antibody [GT1283].
Dilution : 1:100

Anti-GluR2 antibody [GT1283] used in IHC (Paraffin sections) (IHC-P). GTX03195

GTX03195 IHC-P Image

IHC-P analysis of rat brain tissue section using GTX03195 GluR2 antibody [GT1283].
Dilution : 1:100

Anti-GluR2 antibody [GT1283] used in IHC (Paraffin sections) (IHC-P). GTX03195

GTX03195 IHC-P Image

IHC-P analysis of mouse brain tissue section using GTX03195 GluR2 antibody [GT1283].
Blue : DAPI for nuclear staining
Dilution : 1:100

Anti-GluR2 antibody [GT1283] used in IHC (Paraffin sections) (IHC-P). GTX03195

GTX03195 IHC-P Image

IHC-P analysis of rat brain tissue section using GTX03195 GluR2 antibody [GT1283].
Blue : DAPI for nuclear staining
Dilution : 1:100

Anti-GluR2 antibody [GT1283] used in Western Blot (WB). GTX03195

GTX03195 WB Image

WB analysis of various samples using GTX03195 GluR2 antibody [GT1283].
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 439