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GluR4 (phospho Ser862) antibody

Anti-GluR4 (phospho Ser862) antibody used in Western Blot (WB). GTX32189

Cat No. GTX32189

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
Package
100μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

101 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of GluR4. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Glutamate Ionotropic Receptor Ampa Type Subunit 4,Glur4,Glur4C,Glurd,Glua4,Nedsga,Gria4

Cellular Localization

Cell junction,Cell membrane,Cell projection,Dendrite,Postsynaptic cell membrane,Synapse

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-GluR4 (phospho Ser862) antibody used in Western Blot (WB). GTX32189

GTX32189 WB Image

WB analysis of Forskonlin-treated MCF7 (A), mouse brain (B), mouse spleen (C), rat spleen (D) whole cell lysates using GTX32189 GluR4 (phospho Ser862) antibody.

REFERENCE
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REVIEW
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Package List Price ($)
$ 319