GeneTex
United States (US)

GluT1 antibody

GLUT1-antibody-GTX15309-IHC-2_18121410_977.jpg
GLUT1-antibody_IHC-P_GTX15309-1_18121410_952.jpg

Cat No. GTX15309

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:200
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Positive Control

HepG2 cells, esophagous and breast carcinoma
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Solute Carrier Family 2 Member 1,Cse,Dyt17,Dyt18,Dyt9,Eig12,Glut,Glut-1,Glut1,Glut1Ds,Htlvr,Ped,Sdchcn,Slc2A1

Cellular Localization

Cell membrane; Multi-pass membrane protein , Melanosome

Background

Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. Seven types of glucose transport carrier proteins designated as Glut 1 to 7 facilitate glucose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%) all in the molecular weight range of 40 to 60 kDa. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers. Majority of the differences in sequence homology in Glut proteins occur at 4 hydrophilic domains that may play a role in distinct tissue specific pattern of expression and targeting. All Glut proteins are glycosylated at or near the C terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes as in blood brain barrier and blood testis barriers.

Database

Research Area

DATA IMAGES
GLUT1-antibody-GTX15309-IHC-2_18121410_977.jpg

GTX15309 IHC-P Image

GTX15309 staining Glucose Transporter GLUT1 in human esophagous by Immunohistochemistry (FFPE-sections).

GLUT1-antibody_IHC-P_GTX15309-1_18121410_952.jpg

GTX15309 IHC-P Image

Human Esophagus stained with anti-GLUT-1 antibody (GTX15309)

REFERENCE