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Glucocorticoid Receptor antibody [GT1170]

Anti-Glucocorticoid Receptor antibody [GT1170] used in Western Blot (WB). GTX09130

Cat No. GTX09130

Host

Rabbit

Clonality

Monoclonal

Clone Name

GT1170

Isotype

IgG

Application

WB

Reactivity

Human, Mouse, Rat
Package
100 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:2000
Not tested in other applications.

Calculated MW

86 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (pH 7.3) with 0.02% sodium azide, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from hmuan GR

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

nuclear receptor subfamily 3 group C member 1 , GCCR , GCR , GCRST , GR , GRL

Cellular Localization

Nucleus,Mitochondrion,Cytoplasm

Background

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-Glucocorticoid Receptor antibody [GT1170] used in Western Blot (WB). GTX09130

GTX09130 WB Image

WB analysis of various samples using GTX09130 Glucocorticoid Receptor antibody [GT1170].
Dilution : 1:1000
Loading : 25μg

REFERENCE

There are currently no references for Glucocorticoid Receptor antibody [GT1170] (GTX09130). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Glucocorticoid Receptor antibody [GT1170] (GTX09130). Be the first to share your experience with this product.
Package List Price ($)
$ 399