APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 0.5-2.5 μg/ml |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| 0.25 μg/ml |
| 2.5-5.0 μg/ml |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.25 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide selected from the N-terminal region of human GCK
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
glucokinase , FGQTL3 , GK , GLK , HHF3 , HK4 , HKIV , HXKP , LGLK , MODY2
Cellular Localization
Cytoplasm,Nucleus
Background
This gene encodes a member of the hexokinase family of proteins. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. The use of multiple promoters and alternative splicing of this gene result in distinct protein isoforms that exhibit tissue-specific expression in the pancreas and liver. In the pancreas, this enzyme plays a role in glucose-stimulated insulin secretion, while in the liver, this enzyme is important in glucose uptake and conversion to glycogen. Mutations in this gene that alter enzyme activity have been associated with multiple types of diabetes and hyperinsulinemic hypoglycemia. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
|
GTX59598 ICC/IF Image
ICC/IF analysis of HepG2 cells using GTX59598 Glucokinase antibody, N-term.
Green : Primary antibody
Blue : DAPI
|
|
|
GTX59598 IHC-P Image
IHC-P analysis of human breast cancer tissue using Glucokinase antibody, N-term.
|
|
|
GTX59598 WB Image
WB analysis of HepG2 cell lysate (Lane 1) and mouse liver tissue lysate (Lane 2) using GTX59598 Glucokinase antibody, N-term.
|
REFERENCE
There are currently no references for Glucokinase antibody, N-term (GTX59598). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Glucokinase antibody, N-term (GTX59598). Be the first to share your experience with this product.
