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Glutaredoxin 1 antibody

Anti-Glutaredoxin 1 antibody used in Western Blot (WB). GTX02326
Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX02326

Cat No. GTX02326

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
IHC-P 1:10000-1:50000
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.2 μm filtered PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human glutaredoxin-1 / GRX1 / GLRX protein

Purification

Purified by Protein A and Antigen Affinity

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

glutaredoxin , GRX , GRX1

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-Glutaredoxin 1 antibody used in Western Blot (WB). GTX02326

GTX02326 WB Image

WB analysis of Jurkat whole cell lysate (Lane A) using GTX02326 Glutaredoxin 1 antibody.
Dilution : 1:500
Loading : 30 μg

Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX02326

GTX02326 IHC-P Image

IHC-P analysis of human placenta tissue section using GTX02326 Glutaredoxin 1 antibody.
Dilution : 1:50000

REFERENCE

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REVIEW

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