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Glutaredoxin 1 antibody

Anti-Glutaredoxin 1 antibody used in Western Blot (WB). GTX54140
Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140
Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140
Anti-Glutaredoxin 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54140
Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140

Cat No. GTX54140

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human GLRX (NP_001112362.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887844

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

glutaredoxin , GRX , GRX1

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-Glutaredoxin 1 antibody used in Western Blot (WB). GTX54140

GTX54140 WB Image

WB analysis of various sample lysates using GTX54140 Glutaredoxin 1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140

GTX54140 IHC-P Image

IHC-P analysis of human kidney cancer tissue using GTX54140 Glutaredoxin 1 antibody.
Dilution : 1:200

Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140

GTX54140 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX54140 Glutaredoxin 1 antibody.
Dilution : 1:200

Anti-Glutaredoxin 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54140

GTX54140 ICC/IF Image

ICC/IF analysis of C6 cells using GTX54140 Glutaredoxin 1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140

GTX54140 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX54140 Glutaredoxin 1 antibody.
Dilution : 1:200

REFERENCE

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf