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Glutaredoxin 1 antibody

Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140
Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140
Anti-Glutaredoxin 1 antibody used in Western Blot (WB). GTX54140
Anti-Glutaredoxin 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54140
Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140

Cat. No. GTX54140

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Glutaredoxin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human GLRX (NP_001112362.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887844

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glutaredoxin , GRX , GRX1

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140

GTX54140 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX54140 Glutaredoxin 1 antibody.
Dilution : 1:200

Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140

GTX54140 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX54140 Glutaredoxin 1 antibody.
Dilution : 1:200

Anti-Glutaredoxin 1 antibody used in Western Blot (WB). GTX54140

GTX54140 WB Image

WB analysis of various sample lysates using GTX54140 Glutaredoxin 1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Glutaredoxin 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54140

GTX54140 ICC/IF Image

ICC/IF analysis of C6 cells using GTX54140 Glutaredoxin 1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-Glutaredoxin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54140

GTX54140 IHC-P Image

IHC-P analysis of human kidney cancer tissue using GTX54140 Glutaredoxin 1 antibody.
Dilution : 1:200

REFERENCE

Application Reference

M Brzozowa-Zasada et al. Int J Mol Sci 2024; 25 (2) : 1007 A Prognostic Activity of Glutaredoxin 1 Protein (Grx1) in Colon Cancer
Application : WB, IHC-P
Subramani J et al. J Biol Chem 2016; Thioredoxin uses a GSH-independent route to deglutathionylate endothelial nitric oxide synthase and protect against myocardial infarction.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399