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Glutaredoxin 2 antibody, C-term

Anti-Glutaredoxin 2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX81538
Anti-Glutaredoxin 2 antibody, C-term used in Flow cytometry (FACS). GTX81538
Anti-Glutaredoxin 2 antibody, C-term used in Western Blot (WB). GTX81538

Cat. No. GTX81538

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Mouse
Package
400 μl ($399)
See all Glutaredoxin 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:50-1:100
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

18 kDa. ( Note )

Predict Reactivity

Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 120-146 amino acids from the C-terminal region of human GLRX2.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

RRID

AB_11172843

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glutaredoxin 2 , CGI-133 , GRX2

Background

The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-Glutaredoxin 2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX81538

GTX81538 IHC-P Image

IHC-P analysis of human brain tissue using GTX81538 Glutaredoxin 2 antibody, C-term.

Anti-Glutaredoxin 2 antibody, C-term used in Flow cytometry (FACS). GTX81538

GTX81538 FACS Image

FACS analysis of HeLa cells using GTX81538 Glutaredoxin 2 antibody, C-term.
Top histogram : negative control
Bottom histogram : HeLa cells

Anti-Glutaredoxin 2 antibody, C-term used in Western Blot (WB). GTX81538

GTX81538 WB Image

WB analysis of mouse cerebellum tissue lysate (35ug/lane) using GTX81538 Glutaredoxin 2 antibody, C-term.

REFERENCE

Application Reference

M Brzozowa-Zasada et al. Int J Mol Sci 2024; 25 (2) : 1060 Glutaredoxin 2 Protein (Grx2) as an Independent Prognostic Factor Associated with the Survival of Colon Adenocarcinoma Patients
Application : WB, IHC-P
Matsunaga D et al. PLoS One 2016; 11 (10) : e0165150 Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399