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Glypican-3 antibody [YP7]

Anti-Glypican-3 antibody [YP7] used in IHC (Paraffin sections) (IHC-P). GTX03328

Cat. No. GTX03328

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 YP7

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($469)
See all Glypican-3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:25-1:50

Note :

IHC-P
Pretreatment : Citrate Buffer pH 6.0 for 30 min at RT
Not tested in other applications.

Calculated MW

66 kDa. ( Note )

Positive Control

Hepatocellular carcinoma, Thyroid carcinoma

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human GPC3 protein

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glypican 3 , DGSX , GTR2-2 , MXR7 , OCI-5 , SDYS , SGB , SGBS , SGBS1

Cellular Localization

Cell membrane

Background

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES

Anti-Glypican-3 antibody [YP7] used in IHC (Paraffin sections) (IHC-P). GTX03328

GTX03328 IHC-P Image

IHC-P analysis of human hepatocellular carcinoma tissue section using GTX03328 Glypican-3 antibody [YP7].

REFERENCE

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REVIEW

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Package List Price ($)
$ 469