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GnRHR antibody

Anti-GnRHR antibody used in IHC (Paraffin sections) (IHC-P). GTX13011
Anti-GnRHR antibody used in IHC (Paraffin sections) (IHC-P). GTX13011
Anti-GnRHR antibody used in IHC (Paraffin sections) (IHC-P). GTX13011

Cat No. GTX13011

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
25 μg ($289)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:3000
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Rabbit, Sheep, Bovine, Dog, Hamster, Guinea pig, Pig, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Opossum, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GNRHR.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

gonadotropin releasing hormone receptor , GNRHR , GNRHR1 , GRHR , HH7 , LHRHR , LRHR

Cellular Localization

Cell membrane

Background

This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GnRHR antibody used in IHC (Paraffin sections) (IHC-P). GTX13011

GTX13011 IHC-P Image

IHC-P analysis of adrenal gland tissue using GTX13011 GnRHR antibody.

Anti-GnRHR antibody used in IHC (Paraffin sections) (IHC-P). GTX13011

GTX13011 IHC-P Image

IHC-P analysis of brain, pituitary tissue using GTX13011 GnRHR antibody.

Anti-GnRHR antibody used in IHC (Paraffin sections) (IHC-P). GTX13011

GTX13011 IHC-P Image

IHC-P analysis of human pituitary tissue using GTX13011 GnRHR antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf