*Optimal dilutions/concentrations should be determined by the researcher.
Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.
Not tested in other applications.
This antibody has been reported to function as a capture reagent in sandwich ELISA assays for soluble Granzyme B in conjunction with biotin conjugated GB10 (GTX75842) as detection reagent.
Tris buffered saline, 0.09% Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
Purified human Granzyme B.
Protein A purified
From tissue culture supernatant
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Granzyme B , C11 , Ccpi , Cgl-1 , Cgl1 , Csp-B , Cspb , Ctla1 , Ctsgl1 , Hlp , Sect , Gzmb
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]