GeneTex
United States (US)

Growth Hormone antibody [GH-45]

Cat No. GTX27905

Host Mouse
Clonality Monoclonal
Clone Name GH-45
Isotype IgG1
Application ICC/IF, IHC-P
Reactivity Human
APPLICATION

Application Note

ICC: Use at an assay dependant dilution. IHC-P: Use at an assay dependant concentration. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

25 kDa. ( Note )

Specificity/Sensitivity

Specifically reacts with human growth hormone with affinity constant 3.8 x 1010 l /mol. It does not bind human prolactin or any other pituitary hormones.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline pH 7.4 containing 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length native protein (purified) (Human).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Growth Hormone 1,Gh,Gh-N,Ghb5,Ghn,Ighd1B,Hgh-N,Gh1

Background

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq]

Database

Research Area

Package List Price ($)
$ 319