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Growth hormone Receptor antibody

Anti-Growth hormone Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX02538
Anti-Growth hormone Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX02538
Anti-Growth hormone Receptor antibody used in Flow cytometry (FACS). GTX02538

Cat. No. GTX02538

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Rat, Sheep, Pig, Kangaroo rat
Package
100 μl ($399)
See all Growth hormone Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:300-1:1000
IHC-P 1:200-1:400
FACS Assay dependent
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Aqueous buffered solution, 1% BSA, 50% Glycerol

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human GHR (290-340/638).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

growth hormone receptor , GHBP , GHIP

Cellular Localization

Cell membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]

Database

Research Area

DATA IMAGES

Anti-Growth hormone Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX02538

GTX02538 IHC-P Image

IHC-P analysis of tammar wallaby (Macropus eugenii) liver tissue using GTX02538 Growth hormone Receptor antibody.
Dilution : 1:300

Anti-Growth hormone Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX02538

GTX02538 IHC-P Image

IHC-P analysis of rat liver tissue using GTX02538 Growth hormone Receptor antibody.
Dilution : 1:400

Anti-Growth hormone Receptor antibody used in Flow cytometry (FACS). GTX02538

GTX02538 FACS Image

FACS analysis of A549 cells using GTX02538 Growth hormone Receptor antibody.
Green : Primary antibody
Blue : Secondary antibody only control
Dilution : 1:20

REFERENCE

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REVIEW

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Package List Price ($)
$ 399