GeneTex

  • Country / Location Selection

United States (US)

H-Ras antibody

Anti-H-Ras antibody used in Western Blot (WB). GTX55665
Anti-H-Ras antibody used in IHC (Paraffin sections) (IHC-P). GTX55665
Anti-H-Ras antibody used in IHC (Paraffin sections) (IHC-P). GTX55665

Cat. No. GTX55665

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all H-Ras products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide of human HRAS

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

HRas proto-oncogene, GTPase , C-BAS/HAS , C-H-RAS , C-HA-RAS1 , CTLO , H-RASIDX , HAMSV , HRAS1 , KRAS , KRAS2 , Ki-Ras , RASH1 , RASK2 , c-K-ras , c-Ki-ras , p21ras

Cellular Localization

Golgi apparatus,Cytoplasm

Background

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-H-Ras antibody used in Western Blot (WB). GTX55665

GTX55665 WB Image

WB analysis of various sample lysates using GTX55665 H-Ras antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-H-Ras antibody used in IHC (Paraffin sections) (IHC-P). GTX55665

GTX55665 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX55665 H-Ras antibody.
Dilution : 1:100

Anti-H-Ras antibody used in IHC (Paraffin sections) (IHC-P). GTX55665

GTX55665 IHC-P Image

IHC-P analysis of human gastric tissue using GTX55665 H-Ras antibody.
Dilution : 1:100

REFERENCE

There are currently no references for H-Ras antibody (GTX55665). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for H-Ras antibody (GTX55665). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399