GeneTex
United States (US)

HADHB antibody [5C3AB7]

GTX30322_724_ICC-IF_19011519_622.jpg
GTX30322_2123_WB_19011519_804.jpg

Cat No. GTX30322

Host Mouse
Clonality Monoclonal
Clone Name 5C3AB7
Isotype IgG1
Application WB, ICC/IF, IP, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 μg/ml
ICC/IF 1.0 μg/ml
IP Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

51 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

HEPES buffered saline, 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human HADHB

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ECHB,MSTP029,MTPB,TP-BETA

Cellular Localization

Endoplasmic reticulum,Mitochondrion,Mitochondrion inner membrane,Mitochondrion outer membrane

Background

This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

Database

Research Area

DATA IMAGES
GTX30322_724_ICC-IF_19011519_622.jpg

GTX30322 ICC/IF Image

ICC/IF analysis of HDFn cells using GTX30322 HADHB antibody [5C3AB7].
Red : Primary antibody
Blue : Nuclei
Fixation : 4% paraformaldehyde 20 mins
Permeabilization : Triton X-100 (0.1%, 15 min)
Dilution : 1 µg/ml

GTX30322_2123_WB_19011519_804.jpg

GTX30322 WB Image

WB analysis of samples using GTX30322 HADHB antibody [5C3AB7].
Dilution : 1:3000

Package List Price ($)
$ 319