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HAP40 antibody

Anti-HAP40 antibody used in Western Blot (WB). GTX70399

Cat No. GTX70399

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ELISA

Reactivity

Human, Mouse
Package
100 μg ($289)

APPLICATION

Application Note

Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Calculated MW

39 kDa. ( Note )

Specificity/Sensitivity

Reacts with residues 314-325 [DGHGQDTSGQLP] of the 40 kDa mouse HAP40 protein. Co-immunopreciptates Huntingtin protein.

PROPERTIES

Form

Liquid

Buffer

PBS containing 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Affinity purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Coagulation Factor Viii Associated 1 , Dxs522E , F8A , Hap40 , F8A1

Background

HAP40 is a 40-kDa Huntingtin-associated protein. It is likely to contribute to the function of normal huntingtin and is a candidate for involvement in the aberrant nuclear localization of mutant huntingtin found in degenerating neurons in Huntington's disease.

Database

Research Area

DATA IMAGES

Anti-HAP40 antibody used in Western Blot (WB). GTX70399

GTX70399 WB Image

Western blot analysis of HAP40 in mouse brain lysate. Also can co-immunoprecipitate Huntington protein (350 kDa) [not shown on blot].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf