GeneTex
United States (US)

HAX1 antibody, Internal

GTX88468_2289_WB_18121411_620.jpg

Cat No. GTX88468

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-3μg/ml
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88468-PEP).

Specificity/Sensitivity

This antibody is expected to recognize both reported isoforms (NP_006109.2 and NP_001018238.1).
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

Peptide with sequence C-TRHEADSSPRGDPES, from the internal region of the protein sequence according to NP_006109.2; NP_001018238.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

HCLSBP1 Antibody , HS1BP1 Antibody , SCN3 Antibody

Background

The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Database

Research Area

DATA IMAGES
GTX88468_2289_WB_18121411_620.jpg

GTX88468 WB Image

WB analysis of human testis lysate using GTX88468 HAX1 antibody, Internal.
Dilution : 1µg/ml
Loading : 35µg protein in RIPA buffer