*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
HDAC1 Mouse Monoclonal Antibody (4E1) detects endogenous levels of HDAC1
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Synthetic Peptide of HDAC1
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Histone Deacetylase 1,Gon-10,Hd1,Rpd3,Rpd3L1,Hdac1
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]