GeneTex
United States (US)

HDAC1 antibody

GTX31924_3072_WB_20180221_18121410_958.jpg

Cat No. GTX31924

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

Positive Control

Human Brain Tissue Lysate(GTX27918)

Specificity/Sensitivity

HDAC1 antibody is predicted to not cross-react with other members of the HDAC family.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

HDAC1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human HDAC1.The immunogen is located within the last 50 amino acids of HDAC1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Histone Deacetylase 1,Gon-10,Hd1,Rpd3,Rpd3L1,Hdac1

Background

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31924_3072_WB_20180221_18121410_958.jpg

GTX31924 WB Image

WB analysis of human brain tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX31924 HDAC1 antibody.
Working concentration : 1μg/ml

Package List Price ($)
$ 329