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HDAC4 antibody [4A3-H7-C6]

Anti-HDAC4 antibody [4A3-H7-C6] used in Western Blot (WB). GTX49181
Anti-HDAC4 antibody [4A3-H7-C6] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49181

Cat. No. GTX49181

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4A3-H7-C6

Isotype

 IgG2a

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μg ($399)
See all HDAC4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

119 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human HDAC4 protein fragments expressed in E.coli

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

histone deacetylase 4 , AHO3 , BDMR , HA6116 , HD4 , HDAC-4 , HDAC-A , HDACA

Cellular Localization

Nucleus , Cytoplasm

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HDAC4 antibody [4A3-H7-C6] used in Western Blot (WB). GTX49181

GTX49181 WB Image

WB analysis of Jurkat, HeLa and K562 lysates using HDAC4 antibody at a dilution of 1:1,000.

Anti-HDAC4 antibody [4A3-H7-C6] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49181

GTX49181 ICC/IF Image

ICC/IF analysis of HeLa cells using HDAC4 antibody at a dilution of 1:150.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399