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HDAC6 antibody

Anti-HDAC6 antibody used in Western Blot (WB). GTX31926
Anti-HDAC6 antibody used in IHC (Paraffin sections) (IHC-P). GTX31926
Anti-HDAC6 antibody used in IHC (Paraffin sections) (IHC-P). GTX31926

Cat. No. GTX31926

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all HDAC6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

131 kDa. ( Note )

Positive Control

Human Testis Tissue Lysate(GTX15374) , Human Testis Tissue Slide(GTX21748)

Product Note

Multiple isoforms of HDAC6 are known to exist. HDAC6 antibody is predicted to not cross-react with other members of the HDAC family.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

HDAC6 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human HDAC6.The immunogen is located within the last 50 amino acids of HDAC6.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887635

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

histone deacetylase 6 , CPBHM , HD6 , JM21 , PPP1R90

Cellular Localization

Nucleus,Cytoplasm,Cell projection, dendrite

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HDAC6 antibody used in Western Blot (WB). GTX31926

GTX31926 WB Image

WB analysis of human testis tissue lysate using GTX31926 HDAC6 antibody.
Working concentration : 1 μg/ml

Anti-HDAC6 antibody used in IHC (Paraffin sections) (IHC-P). GTX31926

GTX31926 IHC-P Image

IHC-P analysis of human testis tissue using GTX31926 HDAC6 antibody.
Working concentration : 20 μg/ml

Anti-HDAC6 antibody used in IHC (Paraffin sections) (IHC-P). GTX31926

GTX31926 IHC-P Image

IHC-P analysis of human testis tissue using GTX31926 HDAC6 antibody.
Working concentration : 5 μg/ml

REFERENCE

Application Reference

Mazzetti S et al. Front Neurosci 2020; 14 : 624 Phospho-HDAC6 Gathers Into Protein Aggregates in Parkinson's Disease and Atypical Parkinsonisms.
Application : IHC-P
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399