APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS pH7.3, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human HDAC8 (NP_060956.1).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
histone deacetylase 8 , CDA07 , CDLS5 , HD8 , HDACL1 , KDAC8 , MRXS6 , RPD3 , WTS
Cellular Localization
Nucleus,Cytoplasm
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Database
Research Area
DATA IMAGES
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GTX57746 IHC-P Image
IHC-P analysis of rat spinal cord tissue using GTX57746 HDAC8 antibody.
Dilution : 1:100
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GTX57746 IHC-P Image
IHC-P analysis of rat testis tissue using GTX57746 HDAC8 antibody.
Dilution : 1:100
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GTX57746 WB Image
WB analysis of various sample lysates using GTX57746 HDAC8 antibody.
Dilution : 1:1000
Loading : 25μg per lane
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GTX57746 IHC-P Image
IHC-P analysis of human breast cancer tissue using GTX57746 HDAC8 antibody.
Dilution : 1:100
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GTX57746 WB Image
WB analysis of normal (control) and knockout (KO) HeLa cell lysate using GTX57746 HDAC8 antibody.
Dilution : 1:1000
Loading : 25μg per lane
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REFERENCE
There are currently no references for HDAC8 antibody (GTX57746). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for HDAC8 antibody (GTX57746). Be the first to share your experience with this product.
