GeneTex

  • Country / Location Selection

United States (US)

HDAC8 (phospho Ser39) antibody

Anti-HDAC8 (phospho Ser39) antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32364
Anti-HDAC8 (phospho Ser39) antibody used in Western Blot (WB). GTX32364
Anti-HDAC8 (phospho Ser39) antibody used in IHC (Paraffin sections) (IHC-P). GTX32364

Cat. No. GTX32364

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all HDAC8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
ICC/IF 1:100 - 1:500
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of HDAC8. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

histone deacetylase 8 , CDA07 , CDLS5 , HD8 , HDACL1 , KDAC8 , MRXS6 , RPD3 , WTS

Cellular Localization

Nucleus,Cytoplasm

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES

Anti-HDAC8 (phospho Ser39) antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32364

GTX32364 ICC/IF Image

ICC/IF analysis of formalin-fixed A549 cells using GTX32364 HDAC8 (phospho Ser39) antibody.
Red : Primary antibody
Blue : DAPI
Permeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes

Anti-HDAC8 (phospho Ser39) antibody used in Western Blot (WB). GTX32364

GTX32364 WB Image

WB analysis of A549 (A), NIH3T3 (B), rat kidney (C) whole cell lysates using GTX32364 HDAC8 (phospho Ser39) antibody.

Anti-HDAC8 (phospho Ser39) antibody used in IHC (Paraffin sections) (IHC-P). GTX32364

GTX32364 IHC-P Image

IHC-P analysis of formalin fixed human lung cancer tissue section using GTX32364 HDAC8 (phospho Ser39) antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

REFERENCE

There are currently no references for HDAC8 (phospho Ser39) antibody (GTX32364). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for HDAC8 (phospho Ser39) antibody (GTX32364). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399