GeneTex
United States (US)

HES6 antibody

HES6-antibody-GTX87637-WB-1_18122102_829.jpg

Cat No. GTX87637

Host Rabbit
Clonality Polyclonal
Application WB, ELISA
Reactivity Human
APPLICATION

Application Note

We recommend the following starting dilutions:

WB: 1:500~1:1000
ELISA: 1:10000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

24 kDa. ( Note )

Specificity/Sensitivity

HES6 Antibody detects endogenous levels of total HES6 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human HES6.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Hes Family Bhlh Transcription Factor 6,C-Hairy1,Hes-6,Bhlhb41,Bhlhc23,Hes6

Background

Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentation.

Database

DATA IMAGES
HES6-antibody-GTX87637-WB-1_18122102_829.jpg

GTX87637 WB Image

Western blot analysis of extracts from HeLa cells, using HES6 Antibody. The lane on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339