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HEXA antibody, N-term

Anti-HEXA antibody, N-term used in Western Blot (WB). GTX81638
Anti-HEXA antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX81638
Anti-HEXA antibody, N-term used in Western Blot (WB). GTX81638
Anti-HEXA antibody, N-term used in Flow cytometry (FACS). GTX81638

Cat. No. GTX81638

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Mouse
Package
400 μl ($399)
See all HEXA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:50-1:100
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 142-170 amino acids from the N-terminal region of human HEXA.

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

hexosaminidase subunit alpha , TSD

Cellular Localization

Lysosome

Background

This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-HEXA antibody, N-term used in Western Blot (WB). GTX81638

GTX81638 WB Image

WB analysis of mouse liver tissue lysate (35ug/lane) using GTX81638 HEXA antibody, N-term.

Anti-HEXA antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX81638

GTX81638 IHC-P Image

IHC-P analysis of human brain tissue using GTX81638 HEXA antibody, N-term.

Anti-HEXA antibody, N-term used in Western Blot (WB). GTX81638

GTX81638 WB Image

WB analysis of HepG2 cell lysate (35ug/lane) using GTX81638 HEXA antibody, N-term.

Anti-HEXA antibody, N-term used in Flow cytometry (FACS). GTX81638

GTX81638 FACS Image

FACS analysis of HepG2 cells using GTX81638 HEXA antibody, N-term.
Green : primary antibody
Blue : negative control

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399