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HEY1 antibody, C-term

Orthogonal
Anti-HEY1 antibody, C-term used in Western Blot (WB). GTX42614
Anti-HEY1 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX42614
Anti-HEY1 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX42614
Anti-HEY1 antibody, C-term used in Western Blot (WB). GTX42614

Cat. No. GTX42614

Reference 4

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all HEY1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

human lung

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a C-terminal region of Human HEY1

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_625918

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

hes related family bHLH transcription factor with YRPW motif 1 , BHLHb31 , CHF2 , HERP2 , HESR1 , HRT-1 , NERP2 , OAF1 , hHRT1

Cellular Localization

Nucleus

Background

This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HEY1 antibody, C-term used in Western Blot (WB). GTX42614

GTX42614 WB Image

WB analysis of human lung tissue using GTX42614 HEY1 antibody at 1.0μg/ml.

Anti-HEY1 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX42614

GTX42614 IHC-P Image

IHC-P analysis of human kidney tissue using GTX42614 HEY1 antibody at 4.0-8.0μg/ml.

Anti-HEY1 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX42614

GTX42614 IHC-P Image

IHC-P analysis of human lung tissue using GTX42614 HEY1 antibody at 4.0-8.0μg/ml.

Anti-HEY1 antibody, C-term used in Western Blot (WB). GTX42614

GTX42614 WB Image

Orthogonal

The data was published in the journal PLoS One in 2012. PMID: 22715413

REFERENCE

Application Reference

Shao H et al. PLoS One 2021; 16 (3) : e0248260 Converting melanoma-associated fibroblasts into a tumor-suppressive phenotype by increasing intracellular Notch1 pathway activity.
Reactivity : Human
Shao H et al. PLoS One 2015; 10 (11) : e0142815 Notch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion.
Liu ZJ et al. PLoS One 2012; 7 (6) : e38811 Inhibition of fibroblast growth by Notch1 signaling is mediated by induction of Wnt11-dependent WISP-1.
Application : WB
Shao H et al. Oncogene 2011; 30 (42) : 4316-26 Activation of Notch1 signaling in stromal fibroblasts inhibits melanoma growth by upregulating WISP-1.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399