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HGF antibody [24612.111]

Anti-HGF antibody [24612.111] used in Depletion (Depletion). GTX10678

Cat. No. GTX10678

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 24612.111

Isotype

 IgG1

Application

 WB, ELISA, Depletion, Neutralizing/Inhibition

Reactivity

 Human
Package
100 μg ($399)
See all HGF products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2 μg/ml
ELISA 0.5-1 μg/ml
Depletion Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

83 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 5% Trehalose

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

recombinant human HGF.

Purification

Purified immunoglobulin

Conjugation

Unconjugated

RRID

AB_381127

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

hepatocyte growth factor , DFNB39 , F-TCF , HGFB , HPTA , SF

Background

Hepatocyte Growth Factor, also known as Scatter Factor (SF) and Hepatopoietin A, is a pleiotropic growth factor produced by mesodermally derived cells, such as Kupffer cells/macrophages, endothelial cells, and hepatic fat storing cells. HGF stimulates hepatocytes and other epithelial and endothelial cells to various biological actions, including mitogenic, morphogenic and motogenic activity. Anti-Human HGF neutralizes the bioactivity of rhHGF.

Database

Research Area

DATA IMAGES

Anti-HGF antibody [24612.111] used in Depletion (Depletion). GTX10678

GTX10678 Depletion Image

The data was published in the journal PLoS One in 2013. PMID: 24023859

REFERENCE

Application Reference

Ren C et al. Cancer Sci 2024; 115 (2) : 369-384 Cross-talk between gastric cancer and hepatic stellate cells promotes invadopodia formation during liver metastasis.
Yu G et al. PLoS One 2013; 8 (9) : e73312 Hepatic stellate cells secreted hepatocyte growth factor contributes to the chemoresistance of hepatocellular carcinoma.
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399