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HIF1 beta antibody [4C5]

Anti-HIF1 beta antibody [4C5] used in IHC (Paraffin sections) (IHC-P). GTX34039
Anti-HIF1 beta antibody [4C5] used in Western Blot (WB). GTX34039

Cat No. GTX34039

Host Mouse
Clonality Monoclonal
Clone Name 4C5
Isotype IgG1
Application WB, IHC-P
Reactivity Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

Specificity/Sensitivity

HIF-1 β/ARNT Mouse Monoclonal Antibody (4C5) detects endogenous levels of HIF-1 β/ARNT
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant Protein

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Aryl Hydrocarbon Receptor Nuclear Translocator,Hif-1-Beta,Hif-1Beta,Hif1-Beta,Hif1B,Hif1Beta,Tango,Bhlhe2,Arnt

Background

This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]

Database

Research Area

DATA IMAGES
Anti-HIF1 beta antibody [4C5] used in IHC (Paraffin sections) (IHC-P). GTX34039

GTX34039 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Brain Tissue using HIF-1 beta/ARNT Mouse Monoclonal Antibody diluted at 1:200.

Anti-HIF1 beta antibody [4C5] used in Western Blot (WB). GTX34039

GTX34039 WB Image

Western Blot (WB) analysis of Mouse Brain Tissue with HIF-1 beta/ARNT Mouse Monoclonal Antibody diluted at 1:2000.