*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
HIF-1 β/ARNT Mouse Monoclonal Antibody (4C5) detects endogenous levels of HIF-1 β/ARNT
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Aryl Hydrocarbon Receptor Nuclear Translocator,Hif-1-Beta,Hif-1Beta,Hif1-Beta,Hif1B,Hif1Beta,Tango,Bhlhe2,Arnt
This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]