*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
HeLaS3 , Molt-4
Mouse, Rat, Bovine(>80% identity)
1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HIP55. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ABP1 antibody, HIP-55 antibody, SH3P7 antibody, DBNL antibody, SH3 domain-containing protein 7 antibody, drebrin-like protein antibody, cervical SH3P7 antibody, cervical mucin-associated protein antibody, src homology 3 domain-containing protein HIP-55 antibody, drebrin-F antibody, HPK1-interacting protein of 55 kDa antibody, drebrin-like antibody
Cytoplasm , cytoskeleton , Cell projection , lamellipodium
Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
GTX106288 IHC-P Image
Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using HIP55(GTX106288) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
GTX106288 ICC/IF Image
HIP55 antibody [N1], N-term detects DBNL protein at cytoplasm by immunofluorescent analysis.
Sample: HeLa cells were fixed in ice-cold MeOH for 5 min.
Green: DBNL protein stained by HIP55 antibody [N1], N-term (GTX106288) diluted at 1:500.
Blue: Hoechst 33343 staining.
GTX106288 WB Image
Sample(30 μg of whole cell lysate)
10% SDS PAGE
GTX106288 diluted at 1:1500