*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
HIRA (Ab-555) Antibody detects endogenous levels of total HIRA protein.
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
The antiserum was produced against synthesized peptide derived from human HIRA.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TUPLE1, HIRA, TUP1 like enhancer of split protein1, DGCR1, TUP1 like enhancer of split protein 1
Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence.
Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
GTX87684 IHC-P Image
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using HIRA (Ab-555) Antibody. The picture on the right is treated with the synthesized peptide.