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HLA-DPB1 antibody

Anti-HLA-DPB1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54086
Anti-HLA-DPB1 antibody used in Western Blot (WB). GTX54086
Anti-HLA-DPB1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54086

Cat No. GTX54086

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse
Package
100 μl ($379)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 30-225 of human HLA-DPB1 (NP_002112.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

major histocompatibility complex, class II, DP beta 1 , DPB1 , HLA-DP , HLA-DP1B , HLA-DPB

Cellular Localization

Cell membrane; Single-pass type I membrane protein

Background

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HLA-DPB1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54086

GTX54086 IHC-P Image

IHC-P analysis of human stomach tissue using GTX54086 HLA-DPB1 antibody.
Dilution : 1:100

Anti-HLA-DPB1 antibody used in Western Blot (WB). GTX54086

GTX54086 WB Image

WB analysis of various sample lysates using GTX54086 HLA-DPB1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-HLA-DPB1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54086

GTX54086 IHC-P Image

IHC-P analysis of human lymphonodus tissue using GTX54086 HLA-DPB1 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 379