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HLA-DQA1 antibody

Anti-HLA-DQA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX34049
Anti-HLA-DQA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX34049
Anti-HLA-DQA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX34049
Anti-HLA-DQA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX34049

Cat No. GTX34049

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
100 μl ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:50-1:300
Not tested in other applications.

Calculated MW

28|27805 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.02% sodium azide, 50% Glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide from human HLA-DQA1 protein at 21-70 aa.

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CELIAC1,DQA1,HLADQA,HLADQA1,major histocompatibility complex, class II, DQ alpha 1,HLA-DQA1

Cellular Localization

Cell membrane,Endoplasmic reticulum membrane,Endosome membrane,Golgi apparatus,Lysosome membrane,trans-Golgi network membrane,Trans-Golgi network membrane

Background

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HLA-DQA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX34049

GTX34049 IHC-P Image

IHC-P analysis of human spleen tissue using GTX34049 HLA-DQA1 antibody.
Dilution : 1:200

Anti-HLA-DQA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX34049

GTX34049 IHC-P Image

IHC-P analysis of human spleen tissue using GTX34049 HLA-DQA1 antibody.
Dilution : 1:200

Anti-HLA-DQA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX34049

GTX34049 IHC-P Image

IHC-P analysis of human colon tissue using GTX34049 HLA-DQA1 antibody.
Dilution : 1:200

Anti-HLA-DQA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX34049

GTX34049 IHC-P Image

IHC-P analysis of human colon tissue using GTX34049 HLA-DQA1 antibody.
Dilution : 1:200

REFERENCE

There are currently no references for HLA-DQA1 antibody (GTX34049). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for HLA-DQA1 antibody (GTX34049). Be the first to share your experience with this product.
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319