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HLA-DQB2 antibody

Anti-HLA-DQB2 antibody used in IHC (Paraffin sections) (IHC-P). GTX104461
Anti-HLA-DQB2 antibody used in Western Blot (WB). GTX104461

Cat No. GTX104461

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
Package
100 μl ($319),
25 μl ($169)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

30 kDa. ( Note )

Positive Control

K562
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.93 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human HLA-DQB2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

major histocompatibility complex, class II, DQ beta 2 , DQB2 , HLA-DQB1 , HLA-DXB

Cellular Localization

Cell membrane,Endoplasmic reticulum membrane,Endosome membrane,Lysosome membrane

Background

HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq, Oct 2010]

Database

DATA IMAGES
Anti-HLA-DQB2 antibody used in IHC (Paraffin sections) (IHC-P). GTX104461

GTX104461 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using HLA-DQB2(GTX104461) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-HLA-DQB2 antibody used in Western Blot (WB). GTX104461

GTX104461 WB Image

Sample (30 ug of whole cell lysate)
A: K562
12% SDS PAGE
GTX104461 diluted at 1:1000

REFERENCE
There are currently no references for HLA-DQB2 antibody (GTX104461). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for HLA-DQB2 antibody (GTX104461). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169